Ekdizon - Ecdysone

Ekdizon
Ismlar
	IUPAC nomi (22R) -2β, 3β, 14a, 22,25-pentahidroksi-5b-cholest-7-en-6-one
	Tizimli IUPAC nomi (2S,3R,5R,9R,10R,13R,14S,17R)-17- [(2S,3R) -3,6-dihidroksi-6-metilheptan- 2-yl] -2,3,14-trihidroksi-10,13-dimetil- 2,3,4,5,9,11,12,15,16,17 -decahydro- 1H-cyclopenta [a] phenanthren-6-one
Identifikatorlar
CAS raqami	3604-87-3 ;
3D model (JSmol )	Interaktiv rasm;
ChEBI	CHEBI: 16688 ;
ChEMBL	ChEMBL549300 ;
ChemSpider	18130 ;
ECHA ma'lumot kartasi	100.020.692
PubChem CID	19212;
UNII	RH692X7B7B ;
CompTox boshqaruv paneli (EPA)	DTXSID2020553 ;
	InChI InChI = 1S / C27H44O6 / c1-15 (20 (28) 8-9-24 (2,3) 32) 16-7-11-27 (33) 18-12-21 (29) 19-13-22 ( 30) 23 (31) 14-25 (19,4) 17 (18) 6-10-26 (16,27) 5 / h12,15-17,19-20,22-23,28,30-33H, 6-11,13-14H2,1-5H3 / t15-, 16 +, 17-, 19-, 20 +, 22 +, 23-, 25 +, 26 +, 27 + / m0 / s1 Kalit: UPEZCKBFRMILAV-JMZLNJERSA-N ; InChI = 1 / C27H44O6 / c1-15 (20 (28) 8-9-24 (2,3) 32) 16-7-11-27 (33) 18-12-21 (29) 19-13-22 ( 30) 23 (31) 14-25 (19,4) 17 (18) 6-10-26 (16,27) 5 / h12,15-17,19-20,22-23,28,30-33H, 6-11,13-14H2,1-5H3 / t15-, 16 +, 17-, 19-, 20 +, 22 +, 23-, 25 +, 26 +, 27 + / m0 / s1 Kalit: UPEZCKBFRMILAV-JMZLNJERBR;
	Jilmayganlar O = C1 C = C3 / [C @@ H] ([C @] 2 (C [C @ H] (O) [C @ H] (O) C [C @@ H] 12) C) CC [C @] 4 ([C @@] 3 (O) CC [C @@ H] 4 [C @ H] (C) [C @ H] (O) CCC (O) (C) C) C);
Xususiyatlari
Kimyoviy formulalar	C27H44O6
Molyar massa	464,63 g / mol
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	tasdiqlang (nima bu ?)
	Infobox ma'lumotnomalari

Ekdizon a steroidal prohormon asosiy hasharotlar mollash gormon 20-gidroksidizon dan yashiringan protorasik bezlar. Odatda hasharotlarni erituvchi gormonlar (ekdizon va uning gomologlari) deyiladi ekststeroidlar. Ekdysteroidlar molekula gormonlari vazifasini bajaradi artropodlar shuningdek, boshqa tegishli narsalarda ham uchraydi fitna bu erda ular turli xil rollarni o'ynashlari mumkin. Yilda Drosophila melanogaster, ekdizon kontsentratsiyasining oshishi, lichinka talab qiladigan oqsillarni kodlovchi genlarning ekspressionini keltirib chiqaradi va bu xromosoma pufakchalari (yuqori ekspression joylari) hosil bo'lishiga olib keladi. politen xromosomalar. Laboratoriyadagi so'nggi topilmalar Kris Q. Dou Buning yangi rolini topdilar gormon vaqtinchalik tartibga solishda gen o'tishlari ichida asab hujayralari mevali chivin.^[1]

Ekdizon va boshqa ekdysteroidlar ko'plab o'simliklarda asosan himoya vositasi sifatida paydo bo'ladi (toksinlar yoki antifedanslar ) qarshi o'txo'r hasharotlar.^[2] Bular fitoitsisteroidlar bor deb tanildi dorivor qiymati va o'simliklarning bir qismidir adaptogen kabi vositalar Kordiseps, ammo o'simliklardagi ekststeroid kashshofi borligi isbotlangan sitotoksik xususiyatlari.^[3]

Tebufenozid, ostida sotilgan Bayer savdo belgisi MIMIC,^[4] ekdysteroid faolligiga ega, ammo uning kimyoviy tuzilishi ekststeroidlarga unchalik o'xshamaydi.^{[iqtibos kerak ]}

Shuningdek qarang

Ekdizon retseptorlari
PTTH - Metamorfoz tashabbusi gormoni

Tashqi havolalar

Ecdybase, Ecdysone qo'llanmasi - bepul onlayn ecdysteroids ma'lumotlar bazasi

Izohlar

^ Seyid, Muborak Xussayn; Mark, Brendon; Doe, Kris Q. (2017). "Drosophila miya neyroblastlarida vaqtinchalik gen ekspressionining steroid gormoni induktsiyasi neyronal va glial xilma-xillikni keltirib chiqaradi". eLife. 6. doi:10.7554 / eLife.26287. PMC 5403213. PMID 28394252.
^ Dinan L, Savchenko T, Whiting P (2001). "O'simliklarda fitoekststeroidlarning tarqalishi to'g'risida". Uyali va molekulyar hayot haqidagi fanlar. 58 (8): 1121–1132. doi:10.1007 / PL00000926. PMID 11529504.
^ Vang YS, Yang JH, Luo SD, Chjan XB, Li L, molekulalar. 2007; 12 (3): 536-42
^ apvma.gov.au: "Tebufenozid mahsulotidagi Mimic 700 WP insektitsid, Mimic 240 SC insektitsid"

Bu hasharotlar bilan bog'liq maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[1] Seyid, Muborak Xussayn; Mark, Brendon; Doe, Kris Q. (2017). "Drosophila miya neyroblastlarida vaqtinchalik gen ekspressionining steroid gormoni induktsiyasi neyronal va glial xilma-xillikni keltirib chiqaradi". eLife. 6. doi:10.7554 / eLife.26287. PMC 5403213. PMID 28394252.

[2] Dinan L, Savchenko T, Whiting P (2001). "O'simliklarda fitoekststeroidlarning tarqalishi to'g'risida". Uyali va molekulyar hayot haqidagi fanlar. 58 (8): 1121–1132. doi:10.1007 / PL00000926. PMID 11529504.

[3] Vang YS, Yang JH, Luo SD, Chjan XB, Li L, molekulalar. 2007; 12 (3): 536-42

[4] vma.gov.au: "Tebufenozid mahsulotidagi Mimic 700 WP insektitsid, Mimic 240 SC insektitsid"

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[2]

[3]

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Ismlar


IUPAC nomi (22R) -2β, 3β, 14a, 22,25-pentahidroksi-5b-cholest-7-en-6-one
Tizimli IUPAC nomi (2S,3R,5R,9R,10R,13R,14S,17R)-17- [(2S,3R) -3,6-dihidroksi-6-metilheptan- 2-yl] -2,3,14-trihidroksi-10,13-dimetil- 2,3,4,5,9,11,12,15,16,17 -decahydro- 1H-cyclopenta [a] phenanthren-6-one
Identifikatorlar
CAS raqami	3604-87-3^Y
3D model (JSmol )	Interaktiv rasm
ChEBI	CHEBI: 16688^Y
ChEMBL	ChEMBL549300^Y
ChemSpider	18130^Y
ECHA ma'lumot kartasi	100.020.692
PubChem CID	19212
UNII	RH692X7B7B^Y
CompTox boshqaruv paneli (EPA)	DTXSID2020553
InChI InChI = 1S / C27H44O6 / c1-15 (20 (28) 8-9-24 (2,3) 32) 16-7-11-27 (33) 18-12-21 (29) 19-13-22 ( 30) 23 (31) 14-25 (19,4) 17 (18) 6-10-26 (16,27) 5 / h12,15-17,19-20,22-23,28,30-33H, 6-11,13-14H2,1-5H3 / t15-, 16 +, 17-, 19-, 20 +, 22 +, 23-, 25 +, 26 +, 27 + / m0 / s1^Y Kalit: UPEZCKBFRMILAV-JMZLNJERSA-N^Y InChI = 1 / C27H44O6 / c1-15 (20 (28) 8-9-24 (2,3) 32) 16-7-11-27 (33) 18-12-21 (29) 19-13-22 ( 30) 23 (31) 14-25 (19,4) 17 (18) 6-10-26 (16,27) 5 / h12,15-17,19-20,22-23,28,30-33H, 6-11,13-14H2,1-5H3 / t15-, 16 +, 17-, 19-, 20 +, 22 +, 23-, 25 +, 26 +, 27 + / m0 / s1 Kalit: UPEZCKBFRMILAV-JMZLNJERBR
Jilmayganlar O = C1 C = C3 / [C @@ H] ([C @] 2 (C [C @ H] (O) [C @ H] (O) C [C @@ H] 12) C) CC [C @] 4 ([C @@] 3 (O) CC [C @@ H] 4 [C @ H] (C) [C @ H] (O) CCC (O) (C) C) C)
Xususiyatlari
Kimyoviy formulalar	C₂₇H₄₄O₆
Molyar massa	464,63 g / mol
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Y tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari