SYBU - SYBU

SYBU

Identifikatorlar

SYBU, GOLSYN, OCSYN, SNPHL, sintabulin

Tashqi identifikatorlar

OMIM: 611568 MGI: 2442392 HomoloGene: 9838 Generkartalar: SYBU

Gen joylashuvi (odam)

Chr.	Xromosoma 8 (odam)^[1]

Band	8q23.2	Boshlang	109,573,978 bp^[1]
Band	8q23.2	Oxiri	109,691,791 bp^[1]

Gen joylashuvi (Sichqoncha)

Chr.	Xromosoma 15 (sichqoncha)^[2]

Band	15 \| 15 B3.2	Boshlang	44,671,856 bp^[2]
Band	15 \| 15 B3.2	Oxiri	44,788,063 bp^[2]

RNK ekspressioni naqsh

Qo'shimcha ma'lumotni ifodalash ma'lumotlari

Gen ontologiyasi
Molekulyar funktsiya	• mikrotubulani bog'lash • GO: 0001948 oqsil bilan bog'lanish • sintaksin-1 bilan bog'lanish • kinesinni bog'lash
Uyali komponent	• sitoplazma • sitoplazmatik vazikula • membrananing ajralmas komponenti • Golgi membranasi • Golgi apparati • zich tanasi • hujayra ichidagi membrana bilan chegaralangan organelle • sitoskelet • membrana • mikrotubulalar • pufakcha • akson sitoplazmasi
Biologik jarayon	• glyukoza stimuliga uyali javobda ishtirok etadigan insulin sekretsiyasini tartibga solish • mitoxondriyaning aksonal tashilishi • glyukoza stimulyatoriga uyali javoban ishtirok etadigan insulin sekretsiyasini ijobiy tartibga solish • sinaptik faollikni tartibga solish • sinapsning pishishi • anterograd neyronlarning zich yadro pufakchasini tashish
Manbalar:Amigo / QuickGO

Turlar

Inson

Sichqoncha


55638


319613


ENSG00000147642


ENSMUSG00000022340


Q9NX95


Q8BHS8

RefSeq (mRNA)

NM_001099743 NM_001099744 NM_001099745 NM_001099746 NM_001099747
NM_001099748 NM_001099749 NM_001099750 NM_001099751 NM_001099752 NM_001099753 NM_001099754 NM_001099755 NM_001099756 NM_017786 NM_001330596 NM_001363032

NM_001032727 NM_001285840 NM_001285841 NM_001285842 NM_001285843
NM_001285844 NM_176998 NM_178765 NM_001358582 NM_001358583 NM_001358584

RefSeq (oqsil)

NP_001093213 NP_001093214 NP_001093215 NP_001093216 NP_001093217
NP_001093218 NP_001093219 NP_001093220 NP_001093221 NP_001093222 NP_001093223 NP_001093224 NP_001093225 NP_001093226 NP_001317525 NP_060256 NP_001349961

NP_001027899 NP_001272769 NP_001272770 NP_001272771 NP_001272772
NP_001272773 NP_795972 NP_848880 NP_001345511 NP_001345512 NP_001345513

Joylashuv (UCSC)

Chr 8: 109.57 - 109.69 Mb

Chr 15: 44.67 - 44.79 Mb

PubMed qidirmoq

^[3]

^[4]

Insonni ko'rish / tahrirlash

Sichqonchani ko'rish / tahrirlash

Sintabulin, shuningdek, nomi bilan tanilgan SYBU, inson gen.^[5]

Adabiyotlar

^ ^a ^b ^v GRCh38: Ensembl relizi 89: ENSG00000147642 - Ansambl, 2017 yil may
^ ^a ^b ^v GRCm38: Ensembl relizi 89: ENSMUSG00000022340 - Ansambl, 2017 yil may
^ "Human PubMed ma'lumotnomasi:". Milliy Biotexnologiya Axborot Markazi, AQSh Milliy Tibbiyot Kutubxonasi.
^ "Sichqoncha PubMed ma'lumotnomasi:". Milliy Biotexnologiya Axborot Markazi, AQSh Milliy Tibbiyot Kutubxonasi.
^ "Entrez Gen: FLJ20366 gipotetik oqsil FLJ20366".

Qo'shimcha o'qish

Bonaldo MF, Lennon G, Soares MB (1997). "Normallashtirish va ayirish: genlarni kashf etishni osonlashtirish uchun ikkita yondashuv". Genom Res. 6 (9): 791–806. doi:10.1101 / gr.6.9.791. PMID 8889548.
Nagase T, Kikuno R, Ishikava K va boshq. (2000). "Insonning noma'lum genlarini kodlash ketma-ketligini bashorat qilish. XVII. In vitro katta oqsillarni kodlovchi miyadan 100 ta yangi cDNA klonlarining to'liq ketma-ketliklari". DNK rez. 7 (2): 143–50. doi:10.1093 / dnares / 7.2.143. PMID 10819331.
Wistow G, Bernstein SL, Wyatt MK va boshq. (2002). "NEIBank loyihasi uchun insonning RPE / choroid-ning ketma-ketligini tahlil qilish: 6000 dan ortiq ortiqcha bo'lmagan transkriptlar, yangi genlar va qo'shilish variantlari". Mol. Vis. 8: 205–20. PMID 12107410.
Strausberg RL, Feingold EA, Grouse LH va boshq. (2003). "15000 dan ortiq to'liq uzunlikdagi odam va sichqonchani cDNA sekanslarini yaratish va dastlabki tahlil qilish". Proc. Natl. Akad. Ilmiy ish. AQSH. 99 (26): 16899–903. doi:10.1073 / pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikava T va boshq. (2004). "21,243 to'liq uzunlikdagi odam cDNA-larining to'liq ketma-ketligi va tavsifi". Nat. Genet. 36 (1): 40–5. doi:10.1038 / ng1285. PMID 14702039.
Su Q, Cai Q, Gervin S va boshq. (2004). "Sintabulin - bu neytronlarda sintaksinni tashishda ishtirok etadigan mikrotubulalar bilan bog'liq oqsil". Nat. Hujayra biol. 6 (10): 941–53. doi:10.1038 / ncb1169. PMID 15459722. S2CID 6875457.
Funakoshi E, Nakagava KY, Hamano A va boshq. (2005). "Molekulyar klonlash va odamning 8q23 xromosomasida Golgi bilan lokalize qilingan sintaphilin bilan bog'liq oqsil genining xarakteristikasi". Gen. 344: 259–71. doi:10.1016 / j.gene.2004.10.024. PMID 15656992.
Cai Q, Gerwin C, Sheng ZH (2005). "Mitoxondriyani neytral jarayonlar bo'ylab sintebulin vositasida anterograd orqali tashish". J. Hujayra Biol. 170 (6): 959–69. doi:10.1083 / jcb.200506042. PMC 1804288. PMID 16157705.
Kimura K, Vakamatsu A, Suzuki Y va boshq. (2006). "Transkripsiya modulyatsiyasining diversifikatsiyasi: inson genlarining muqobil alternativ targ'ibotchilarini keng ko'lamda aniqlash va tavsiflash". Genom Res. 16 (1): 55–65. doi:10.1101 / gr.4039406. PMC 1356129. PMID 16344560.
Funakoshi E, Fukui M, Hamano A va boshq. (2006). "Sichqoncha miyasi rivojlanishi davomida m-Golsin / Sintabulin genining ekspressioni". Neurosci. Lett. 403 (3): 244–9. doi:10.1016 / j.neulet.2006.04.061. PMID 16750881. S2CID 40236853.
Cai Q, Pan PY, Sheng ZH (2007). "Sintabulin-kinesin-1 oilasi a'zosi 5B-vositali aksonal transport faollikka bog'liq presinaptik yig'ilishga yordam beradi". J. Neurosci. 27 (27): 7284–96. doi:10.1523 / JNEUROSCI.0731-07.2007. PMC 6794594. PMID 17611281.

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