Spilantol - Spilanthol

Spilantol
Ismlar
	IUPAC nomi (2E,6Z,8E)-N-Izobutil-2,6,8-dekatrienamid
	Boshqa ismlar Affinin
Identifikatorlar
CAS raqami	25394-57-4 ;
3D model (JSmol )	Interaktiv rasm;
ChemSpider	4509783;
PubChem CID	5353001;
UNII	4W9L3S4856 ;
CompTox boshqaruv paneli (EPA)	DTXSID90893963 ;
	InChI InChI = 1S / C14H23NO / c1-4-5-6-7-8-9-10-11-14 (16) 15-12-13 (2) 3 / h4-7,10-11,13H, 8- 9,12H2,1-3H3, (H, 15,16) / b5-4 +, 7-6-, 11-10 + Kalit: BXOCHUWSGYYSFW-HVWOQQCMSA-N; InChI = 1 / C14H23NO / c1-4-5-6-7-8-9-10-11-14 (16) 15-12-13 (2) 3 / h4-7,10-11,13H, 8- 9,12H2,1-3H3, (H, 15,16) / b5-4 +, 7-6-, 11-10 + Kalit: BXOCHUWSGYYSFW-HVWOQQCMBC;
	Jilmayganlar O = C (/ C = C / CC / C = C C = C C) NCC (C) C;
Xususiyatlari
Kimyoviy formulalar	C14H23NO
Molyar massa	221.344 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

Spilantol a yog 'kislotasi amidi dan ajratilgan Acmella oleracea.^[1] Bu uchun javobgar deb ishoniladi mahalliy og'riqsizlantirish o'simlikning xususiyatlari.^[2]

Spilantol inson terisiga singib ketadi ^[3] va og'izda yonoqlarning ichki qoplamasi (bukkal shilliq qavat ),^[4] natijada lokal, shuningdek tizimli farmakologik konsentratsiyalar paydo bo'ladi.

Shuningdek qarang

Gidroksi alfa sanshool

Adabiyotlar

^ Ramsevak, RS; Erikson, AJ; Nair, MG (1999). "Spilanthes acmella gul kurtaklaridan biofaol N-izobutilamidlar". Fitokimyo. 51 (6): 729–32. doi:10.1016 / S0031-9422 (99) 00101-6. PMID 10389272.
^ Spelman, Kevin; Depoix, Delphine; Makkrey, Megan; Mouray, Elisabet; Grelli, Filipp (2011). "An'anaviy tibbiyot akmella va alkilamidlar spilantol va undeca-2E-ene-8,10-dinoik kislota izobutilamidni in vitro va in vivo antimalarial faollikni namoyish etadi". Fitoterapiya tadqiqotlari. 25 (7): 1098–101. doi:10.1002 / ptr.3395. PMC 3374932. PMID 22692989.
^ Boonen, Jente; Baert, Bram; Rosh, Natali; Burvenich, nasroniy; De Spiegeleer, Bart (2010). "Spilanthes acmella (Compositae) ekstraktlaridan N-alkilamid spilantol (affinin) ning transdermal harakati". Etnofarmakologiya jurnali. 127 (1): 77–84. doi:10.1016 / j.jep.2009.09.046. PMID 19808085.
^ Boonen, Jente; Baert, Bram; Burvenich, nasroniy; Bondeel, Fillip; De Saeger, Sara; De Spiegeleer, Bart (2010). "Spilanthes akmella ekstraktidagi N-alkilamidlarning LC-MS profillanishi va uning asosiy biofaol spilantolining transmukozal harakati". Farmatsevtika va biomedikal tahlillar jurnali. 53 (3): 243–249. doi:10.1016 / j.jpba.2010.02.010. PMID 20227845.

Haqida ushbu maqola organik birikma a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[1] Ramsevak, RS; Erikson, AJ; Nair, MG (1999). "Spilanthes acmella gul kurtaklaridan biofaol N-izobutilamidlar". Fitokimyo. 51 (6): 729–32. doi:10.1016 / S0031-9422 (99) 00101-6. PMID 10389272.

[2] Spelman, Kevin; Depoix, Delphine; Makkrey, Megan; Mouray, Elisabet; Grelli, Filipp (2011). "An'anaviy tibbiyot akmella va alkilamidlar spilantol va undeca-2E-ene-8,10-dinoik kislota izobutilamidni in vitro va in vivo antimalarial faollikni namoyish etadi". Fitoterapiya tadqiqotlari. 25 (7): 1098–101. doi:10.1002 / ptr.3395. PMC 3374932. PMID 22692989.

[3] Boonen, Jente; Baert, Bram; Rosh, Natali; Burvenich, nasroniy; De Spiegeleer, Bart (2010). "Spilanthes acmella (Compositae) ekstraktlaridan N-alkilamid spilantol (affinin) ning transdermal harakati". Etnofarmakologiya jurnali. 127 (1): 77–84. doi:10.1016 / j.jep.2009.09.046. PMID 19808085.

[4] Boonen, Jente; Baert, Bram; Burvenich, nasroniy; Bondeel, Fillip; De Saeger, Sara; De Spiegeleer, Bart (2010). "Spilanthes akmella ekstraktidagi N-alkilamidlarning LC-MS profillanishi va uning asosiy biofaol spilantolining transmukozal harakati". Farmatsevtika va biomedikal tahlillar jurnali. 53 (3): 243–249. doi:10.1016 / j.jpba.2010.02.010. PMID 20227845.

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Ismlar

IUPAC nomi (2E,6Z,8E)-N-Izobutil-2,6,8-dekatrienamid
Boshqa ismlar Affinin
Identifikatorlar
CAS raqami	25394-57-4^Y
3D model (JSmol )	Interaktiv rasm
ChemSpider	4509783
PubChem CID	5353001
UNII	4W9L3S4856^Y
CompTox boshqaruv paneli (EPA)	DTXSID90893963
InChI InChI = 1S / C14H23NO / c1-4-5-6-7-8-9-10-11-14 (16) 15-12-13 (2) 3 / h4-7,10-11,13H, 8- 9,12H2,1-3H3, (H, 15,16) / b5-4 +, 7-6-, 11-10 + Kalit: BXOCHUWSGYYSFW-HVWOQQCMSA-N InChI = 1 / C14H23NO / c1-4-5-6-7-8-9-10-11-14 (16) 15-12-13 (2) 3 / h4-7,10-11,13H, 8- 9,12H2,1-3H3, (H, 15,16) / b5-4 +, 7-6-, 11-10 + Kalit: BXOCHUWSGYYSFW-HVWOQQCMBC
Jilmayganlar O = C (/ C = C / CC / C = C C = C C) NCC (C) C
Xususiyatlari
Kimyoviy formulalar	C₁₄H₂₃NO
Molyar massa	221.344 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari