RB-3007 - RB-3007 - Wikipedia

RB-3007
Ismlar
	IUPAC nomi Benzil (2S) -2 - [[(2S) -2 - [[2-atsetilsülfaniletoksi - [(R) -amino (fenil) metil] fosforil] metil] -3- (4-fenilfenil) propanoil] amino] propanoat
	Boshqa ismlar RB3007, LS-15768
Identifikatorlar
3D model (JSmol )	Interaktiv rasm;
PubChem CID	11072779;
	InChI InChI = 1S / C37H41N2O6PS / c1-27 (37 (42) 44-25-30-12-6-3-7-13-30) 39-36 (41) 34 (24-29-18-20-32 ( 21-19-29) 31-14-8-4-9-15-31) 26-46 (43,45-22-23-47-28 (2) 40) 35 (38) 33-16-10- 5-11-17-33 / h3-21,27,34-35H, 22-26,38H2,1-2H3, (H, 39,41) / t27-, 34 +, 35 +, 46? / M0 / s1 Kalit: PYJMLILRVYLUHW-UNCDKACKSA-N;
	Jilmayganlar C [C @ H] (bosimining ko'tarilishi (= O) [C @ H] (CC1 = CC = C (C = C1) C1 = CC = CC = C1) CP (= O) (OCCSC (C) = O) [ C @@ H] (N) C1 = CC = CC = C1) C (= O) OCC1 = CC = CC = C1;
Xususiyatlari
Kimyoviy formulalar	C37H41N2O6PS
Molyar massa	672.78 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

RB-3007 ning og'zaki faol analogidir RB-101. U ilmiy tadqiqotlarda ishlatiladigan enkefalinaza inhibitori vazifasini bajaradi.^[1]^[2]

Shuningdek qarang

RB-101 - nafas olish depressiyasiz og'riq qoldiruvchi vositani ishlab chiqaradigan enkefalinaz inhibitori
D / DL-fenilalanin - Enkefalinning parchalanishining D-fenilalanin tiqilishi DL-Fenilalaninning taniqli analjezik ta'siriga sabab bo'lishi mumkin.
Ratsekadotril - periferik enkefalinaza inhibitori vazifasini bajaradigan antidiareal preparat
Ekadotril - neytral endopeptidaza inhibitori

^ Tanavala, V .; Qadam, V .; Ghosh, R. (2008 yil 1 oktyabr). "Enkefalinaz inhibitörleri: Og'riqni boshqarish uchun potentsial vositalar". Giyohvandlikning dolzarb maqsadlari. 9 (10): 887–894. doi:10.2174/138945008785909356. PMID 18855623.
^ Noble, Florensiya; Roques, Bernard P (2007 yil 17-yanvar). "Endogen enkefalin katabolizmini yangi analjezik va antidepressant dorilarga tabiiy yondoshish sifatida himoya qilish". Terapevtik maqsadlar bo'yicha mutaxassislarning fikri. 11 (2): 145–159. doi:10.1517/14728222.11.2.145. PMID 17227231.

Ismlar

IUPAC nomi Benzil (2S) -2 - [[(2S) -2 - [[2-atsetilsülfaniletoksi - [(R) -amino (fenil) metil] fosforil] metil] -3- (4-fenilfenil) propanoil] amino] propanoat
Boshqa ismlar RB3007, LS-15768
Identifikatorlar
3D model (JSmol )	Interaktiv rasm
PubChem CID	11072779
InChI InChI = 1S / C37H41N2O6PS / c1-27 (37 (42) 44-25-30-12-6-3-7-13-30) 39-36 (41) 34 (24-29-18-20-32 ( 21-19-29) 31-14-8-4-9-15-31) 26-46 (43,45-22-23-47-28 (2) 40) 35 (38) 33-16-10- 5-11-17-33 / h3-21,27,34-35H, 22-26,38H2,1-2H3, (H, 39,41) / t27-, 34 +, 35 +, 46? / M0 / s1 Kalit: PYJMLILRVYLUHW-UNCDKACKSA-N
Jilmayganlar C [C @ H] (bosimining ko'tarilishi (= O) [C @ H] (CC1 = CC = C (C = C1) C1 = CC = CC = C1) CP (= O) (OCCSC (C) = O) [ C @@ H] (N) C1 = CC = CC = C1) C (= O) OCC1 = CC = CC = C1
Xususiyatlari
Kimyoviy formulalar	C₃₇H₄₁N₂O₆PS
Molyar massa	672.78 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari