Amoskanat - Amoscanate

Amoskanat
Ismlar
	IUPAC nomi 4-izotiyosiyanato-N- (4-nitrofenil) anilin
	Boshqa ismlar 4-izotiyosiyanato-4b-nitrodifenilamin; Nitiosiyamin
Identifikatorlar
CAS raqami	26328-53-0 ;
3D model (JSmol )	Interaktiv rasm; Interaktiv rasm;
ChEBI	CHEBI: 38944 ;
ChEMBL	ChEMBL93385 ;
ChemSpider	30904 ;
PubChem CID	33488;
UNII	X0MK46CVRB ;
CompTox boshqaruv paneli (EPA)	DTXSID90180946 ;
	InChI InChI = 1S / C13H9N3O2S / c17-16 (18) 13-7-5-12 (6-8-13) 15-11-3-1-10 (2-4-11) 14-9-19 / h1- 8,15H Kalit: DKVNAGXPRSYHLB-UHFFFAOYSA-N ; InChI = 1 / C13H9N3O2S / c17-16 (18) 13-7-5-12 (6-8-13) 15-11-3-1-10 (2-4-11) 14-9-19 / h1- 8,15H;
	Jilmayganlar O = N (= O) c1ccc (Nc2ccc (cc2) N = C = S) cc1; [O -] [N +] (= O) c1ccc (cc1) Nc2ccc (N = C = S) cc2;
Xususiyatlari
Kimyoviy formulalar	C13H9N3O2S
Molyar massa	271.29 g · mol−1
Erish nuqtasi	204 dan 206 ° C gacha (399 dan 403 ° F; 477 dan 479 K gacha)
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	tasdiqlang (nima bu ?)
	Infobox ma'lumotnomalari

Amoskanat (KARVONSAROY ), shuningdek, nomi bilan tanilgan nitiosiyamin, eksperimental hisoblanadi anthelmintic agenti aril izotiyosiyanat to'rt asosiy turga qarshi hayvonlarda juda samarali ekanligi aniqlangan sinf shistosomalar odamlarga yuqadigan,^[1] va shuningdek, qarshi juda faol ankilomit infektsiya.^[2]^[3] Shu bilan birga, yuqori dozalarda laboratoriya hayvonlarida sezilarli darajada jigar toksikligi kuzatildi. The efir analog amoskanat, nitroskanat, ichida ishlatiladi veterinariya tibbiyoti anthelmintic sifatida.

Amoskanat tomonidan ishlab chiqilgan Ciba.^[4]^[5]

Adabiyotlar

^ Shapiro TA, WB JB, Talalay P va boshq. (1986 yil sentyabr). "Sog'lom erkak ko'ngillilarda amoskanatning klinik baholanishi". Am. J. Trop. Med. Hyg. 35 (5): 945–53. PMID 3766854.
^ Doshi JC, Vaidya AB, Sen HG, Mankodi NA, Nair CN, Grewal RS (iyul 1977). "Ankilomit infektsiyasini davolash uchun yangi anthelmintic, 4-izotiosiyanato-4'-nitrodifenilamin (C.9333-Go / CGP 4540) ning klinik sinovlari". Am. J. Trop. Med. Hyg. 26 (4): 636–9. PMID 889004.
^ Singh DS, Bala-Subramaniam R, Bhatia VN, Kumar V, Chandrasekar S (1981). "Go.9333 (Ciba-Geigy) birikmasining ankilomateriya zararlanishida samaradorligini o'rganish". Kimyoviy terapiya. 27 (3): 220–3. doi:10.1159/000237981. PMID 7014129.
^ Vaidya AB, Sen HG, Mankodi NA, Pol T, Buyuk Britaniyaning Shet shahri (1977 yil avgust). "Yangi anthelmintic 1-bosqichga chidamlilik va 4-izotiyosiyanato-4'-nitrodifenilamin (C.9333-Go / CGP 4540) bilan dozani o'rganish". Br J Clin Farmakol. 4 (4): 463–7. doi:10.1111 / j.1365-2125.1977.tb00763.x. PMC 1429051. PMID 901739.
^ Sharma S (1987). "Gelmint kasalliklari". Jaker E (tahrir). Giyohvand moddalarni tadqiq qilishda taraqqiyot. 31. Boston: Birxauzer. ISBN 3-7643-1837-6. 2008 yil 10 sentyabrda olingan Google Book Search.

Bu infektsiyaga qarshi dori maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[1] Shapiro TA, WB JB, Talalay P va boshq. (1986 yil sentyabr). "Sog'lom erkak ko'ngillilarda amoskanatning klinik baholanishi". Am. J. Trop. Med. Hyg. 35 (5): 945–53. PMID 3766854.

[2] Doshi JC, Vaidya AB, Sen HG, Mankodi NA, Nair CN, Grewal RS (iyul 1977). "Ankilomit infektsiyasini davolash uchun yangi anthelmintic, 4-izotiosiyanato-4'-nitrodifenilamin (C.9333-Go / CGP 4540) ning klinik sinovlari". Am. J. Trop. Med. Hyg. 26 (4): 636–9. PMID 889004.

[3] Singh DS, Bala-Subramaniam R, Bhatia VN, Kumar V, Chandrasekar S (1981). "Go.9333 (Ciba-Geigy) birikmasining ankilomateriya zararlanishida samaradorligini o'rganish". Kimyoviy terapiya. 27 (3): 220–3. doi:10.1159/000237981. PMID 7014129.

[4] Vaidya AB, Sen HG, Mankodi NA, Pol T, Buyuk Britaniyaning Shet shahri (1977 yil avgust). "Yangi anthelmintic 1-bosqichga chidamlilik va 4-izotiyosiyanato-4'-nitrodifenilamin (C.9333-Go / CGP 4540) bilan dozani o'rganish". Br J Clin Farmakol. 4 (4): 463–7. doi:10.1111 / j.1365-2125.1977.tb00763.x. PMC 1429051. PMID 901739.

[5] Sharma S (1987). "Gelmint kasalliklari". Jaker E (tahrir). Giyohvand moddalarni tadqiq qilishda taraqqiyot. 31. Boston: Birxauzer. ISBN 3-7643-1837-6. 2008 yil 10 sentyabrda olingan Google Book Search.

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Ismlar


IUPAC nomi 4-izotiyosiyanato-N- (4-nitrofenil) anilin
Boshqa ismlar 4-izotiyosiyanato-4b-nitrodifenilamin Nitiosiyamin
Identifikatorlar
CAS raqami	26328-53-0^Y
3D model (JSmol )	Interaktiv rasm Interaktiv rasm
ChEBI	CHEBI: 38944^Y
ChEMBL	ChEMBL93385^Y
ChemSpider	30904^Y
PubChem CID	33488
UNII	X0MK46CVRB^Y
CompTox boshqaruv paneli (EPA)	DTXSID90180946
InChI InChI = 1S / C13H9N3O2S / c17-16 (18) 13-7-5-12 (6-8-13) 15-11-3-1-10 (2-4-11) 14-9-19 / h1- 8,15H^Y Kalit: DKVNAGXPRSYHLB-UHFFFAOYSA-N^Y InChI = 1 / C13H9N3O2S / c17-16 (18) 13-7-5-12 (6-8-13) 15-11-3-1-10 (2-4-11) 14-9-19 / h1- 8,15H
Jilmayganlar O = N (= O) c1ccc (Nc2ccc (cc2) N = C = S) cc1 [O -] [N +] (= O) c1ccc (cc1) Nc2ccc (N = C = S) cc2
Xususiyatlari
Kimyoviy formulalar	C₁₃H₉N₃O₂S
Molyar massa	271.29 g · mol⁻¹
Erish nuqtasi	204 dan 206 ° C gacha (399 dan 403 ° F; 477 dan 479 K gacha)
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Y tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari