Sklareol - Sclareol - Wikipedia

Sklareol
Ismlar
	IUPAC nomi (1R,2R, 4aS, 8aS)-1-[(3R) -3-gidroksi-3-metilpent-4-enil] -2,5,5,8a-tetrametil-3,4,4a, 6,7,8-geksahidro-1H-naftalin-2-ol
	Boshqa ismlar Labd-14-ene-8,13-diol
Identifikatorlar
CAS raqami	515-03-7 ;
3D model (JSmol )	Interaktiv rasm;
ChEBI	CHEBI: 9053 ;
ChemSpider	143282 ;
ECHA ma'lumot kartasi	100.007.450
KEGG	C09183 ;
PubChem CID	163263;
UNII	B607NP0Q8Y ;
CompTox boshqaruv paneli (EPA)	DTXSID0047111 ;
	InChI InChI = 1S / C20H36O2 / c1-7-18 (4,21) 13-9-16-19 (5) 12-8-11-17 (2,3) 15 (19) 10-14-20 (16, 6) 22 / h7,15-16,21-22H, 1,8-14H2,2-6H3 / t15-, 16 +, 18-, 19-, 20 + / m0 / s1 Kalit: XVULBTBTFGYVRC-HHUCQEJWSA-N ; InChI = 1 / C20H36O2 / c1-7-18 (4,21) 13-9-16-19 (5) 12-8-11-17 (2,3) 15 (19) 10-14-20 (16, 6) 22 / h7,15-16,21-22H, 1,8-14H2,2-6H3 / t15-, 16 +, 18-, 19-, 20 + / m0 / s1 Kalit: XVULBTBTFGYVRC-HHUCQEJWBX;
	Jilmayganlar CC1 (C) CCC [C @@] 2 (C) [C @@] 1 ([H]) CC [C @@] (C) (O) [C @@ H] 2CC [C @] (O ) (C) C = C;
Xususiyatlari
Kimyoviy formulalar	C20H36O2
Molyar massa	308.506 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	tasdiqlang (nima bu ?)
	Infobox ma'lumotnomalari

Sklareol ichida joylashgan xushbo'y kimyoviy birikma Salvia sklarea, bu uning nomini keltirib chiqaradi. Bisiklik sifatida tasniflanadi diterpen spirtli ichimliklar. Bu shirin, balzam hidiga ega bo'lgan sarg'ish rangli qattiq rang.^[1] Sclareol shuningdek, odamning leykemik hujayralari va yo'g'on ichak saraton hujayralarini o'ldirishga qodir apoptoz.^[2]^[3]

Adabiyotlar

^ Good Scents Company
^ Dimas, Kostas; Kokkinopulos, Dimitrios; Demetos, Kostas; Vaos, Bazilios; Marselos, Marios; Malamalar, Mixalis; Tsavaras, Teodoros (1999). "Sklereolning o'sishi va inson leykemik hujayra chiziqlarining hujayra tsiklining rivojlanishiga ta'siri". Leykemiya tadqiqotlari. 23 (3): 217–234. doi:10.1016 / S0145-2126 (98) 00134-9. PMID 10071073.
^ K. Dimas; Xatziantoniou, S; Tseleni, S; Xon, H; Georgopulos, A; Alevizopulos, K; Wyche, JH; Pantazis, P; Demetzos, C (2007). "Sclareol in vitro odamning HCT116 yo'g'on ichak saraton hujayralarida apoptozni keltirib chiqaradi va immunitet tanqisligi bo'lgan sichqonlarda HCT116 o'simtasining o'sishini bostiradi". Apoptoz. 12 (4): 685–694. doi:10.1007 / s10495-006-0026-8. PMID 17260186.

[1] Good Scents Company

[2] Dimas, Kostas; Kokkinopulos, Dimitrios; Demetos, Kostas; Vaos, Bazilios; Marselos, Marios; Malamalar, Mixalis; Tsavaras, Teodoros (1999). "Sklereolning o'sishi va inson leykemik hujayra chiziqlarining hujayra tsiklining rivojlanishiga ta'siri". Leykemiya tadqiqotlari. 23 (3): 217–234. doi:10.1016 / S0145-2126 (98) 00134-9. PMID 10071073.

[3] K. Dimas; Xatziantoniou, S; Tseleni, S; Xon, H; Georgopulos, A; Alevizopulos, K; Wyche, JH; Pantazis, P; Demetzos, C (2007). "Sclareol in vitro odamning HCT116 yo'g'on ichak saraton hujayralarida apoptozni keltirib chiqaradi va immunitet tanqisligi bo'lgan sichqonlarda HCT116 o'simtasining o'sishini bostiradi". Apoptoz. 12 (4): 685–694. doi:10.1007 / s10495-006-0026-8. PMID 17260186.

[1]

[2]

[3]

Ismlar

IUPAC nomi (1R,2R, 4aS, 8aS)-1-[(3R) -3-gidroksi-3-metilpent-4-enil] -2,5,5,8a-tetrametil-3,4,4a, 6,7,8-geksahidro-1H-naftalin-2-ol
Boshqa ismlar Labd-14-ene-8,13-diol
Identifikatorlar
CAS raqami	515-03-7^Y
3D model (JSmol )	Interaktiv rasm
ChEBI	CHEBI: 9053^N
ChemSpider	143282^N
ECHA ma'lumot kartasi	100.007.450
KEGG	C09183^N
PubChem CID	163263
UNII	B607NP0Q8Y^Y
CompTox boshqaruv paneli (EPA)	DTXSID0047111
InChI InChI = 1S / C20H36O2 / c1-7-18 (4,21) 13-9-16-19 (5) 12-8-11-17 (2,3) 15 (19) 10-14-20 (16, 6) 22 / h7,15-16,21-22H, 1,8-14H2,2-6H3 / t15-, 16 +, 18-, 19-, 20 + / m0 / s1^N Kalit: XVULBTBTFGYVRC-HHUCQEJWSA-N^N InChI = 1 / C20H36O2 / c1-7-18 (4,21) 13-9-16-19 (5) 12-8-11-17 (2,3) 15 (19) 10-14-20 (16, 6) 22 / h7,15-16,21-22H, 1,8-14H2,2-6H3 / t15-, 16 +, 18-, 19-, 20 + / m0 / s1 Kalit: XVULBTBTFGYVRC-HHUCQEJWBX
Jilmayganlar CC1 (C) CCC [C @@] 2 (C) [C @@] 1 ([H]) CC [C @@] (C) (O) [C @@ H] 2CC [C @] (O ) (C) C = C
Xususiyatlari
Kimyoviy formulalar	C₂₀H₃₆O₂
Molyar massa	308.506 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
N tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari