Kineloran - Quinelorane

Kineloran
Identifikatorlar
	IUPAC nomi (5aR, 9aR) -6-propil-5a, 7,8,9,9a, 10-heksahidro-5H-pirido [2,3-g] kinazolin-2-amin;
CAS raqami	97548-97-5 ;
PubChem CID	57242;
IUPHAR / BPS	954;
ChemSpider	51604 ;
UNII	Z0X4VT3Y1Q;
KEGG	D05677 ;
ChEMBL	ChEMBL155731 ;
CompTox boshqaruv paneli (EPA)	DTXSID4046315 ;
Kimyoviy va fizik ma'lumotlar
Formula	C14H22N4
Molyar massa	246.358 g · mol−1
3D model (JSmol )	Interaktiv rasm;
	Jilmayganlar CCCN1CCC [C @ H] 2 [C @ H] 1CC3 = CN = C (N = C3C2) N;
	InChI InChI = 1S / C14H22N4 / c1-2-5-18-6-3-4-10-7-12-11 (8-13 (10) 18) 9-16-14 (15) 17-12 / h9- 10,13H, 2-8H2,1H3, (H2,15,16,17) / t10-, 13- / m1 / s1 ; Kalit: TUFADSGTJUOBEH-ZWNOBZJWSA-N ;
	(bu nima?) (tasdiqlash)

Kineloran kabi harakat qiladigan dori dopamin agonisti uchun D.₂^[1]^[2]^[3] va D.₃ retseptorlari.

Shuningdek qarang

^ Caine SB, Negus SS, Mello NK, Patel S, Bristow L, Kulagowski J, Vallone D, Saiardi A, Borrelli E (aprel 2002). "Dopamin D2 o'xshash retseptorlarining kokainni o'z-o'zini boshqarishda ahamiyati: D2 retseptorlari mutant sichqonlari va yangi D2 retseptorlari antagonistlari bilan tadqiqotlar". Neuroscience jurnali. 22 (7): 2977–88. doi:10.1523 / JNEUROSCI.22-07-02977.2002. PMC 6758322. PMID 11923462.
^ Gasior M, Paronis CA, Bergman J (yanvar 2004). "Dopaminerjik dorilar tomonidan tanlangan xatti-harakatni bir vaqtda, vena ichiga tomchilatib yuborish va maymunlarda ovqat etkazib berish asosida o'zgartirish". Farmakologiya va eksperimental terapiya jurnali. 308 (1): 249–59. doi:10.1124 / jpet.103.052795. PMID 14563783.
^ Bruks JM, Sarter M, Bruno JP (sentyabr 2007). "Yadro akumbensidagi D2 ga o'xshash retseptorlar prefrontal korteksdagi atsetilxolin tarqalishini salbiy ravishda modulyatsiya qiladi".. Neyrofarmakologiya. 53 (3): 455–63. doi:10.1016 / j.neuropharm.2007.06.006. PMC 2000917. PMID 17681559.

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Identifikatorlar

IUPAC nomi (5aR, 9aR) -6-propil-5a, 7,8,9,9a, 10-heksahidro-5H-pirido [2,3-g] kinazolin-2-amin
CAS raqami	97548-97-5^Y
PubChem CID	57242
IUPHAR / BPS	954
ChemSpider	51604^N
UNII	Z0X4VT3Y1Q
KEGG	D05677^Y
ChEMBL	ChEMBL155731^N
CompTox boshqaruv paneli (EPA)	DTXSID4046315
Kimyoviy va fizik ma'lumotlar
Formula	C₁₄H₂₂N₄
Molyar massa	246.358 g · mol⁻¹
3D model (JSmol )	Interaktiv rasm
Jilmayganlar CCCN1CCC [C @ H] 2 [C @ H] 1CC3 = CN = C (N = C3C2) N
InChI InChI = 1S / C14H22N4 / c1-2-5-18-6-3-4-10-7-12-11 (8-13 (10) 18) 9-16-14 (15) 17-12 / h9- 10,13H, 2-8H2,1H3, (H2,15,16,17) / t10-, 13- / m1 / s1^N Kalit: TUFADSGTJUOBEH-ZWNOBZJWSA-N^N
^NY (bu nima?) (tasdiqlash)