Silostamid - Cilostamide

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Manbalarni toping: "Silostamid" – Yangiliklar · gazetalar · kitoblar · olim · JSTOR (2017 yil yanvar) (Ushbu shablon xabarini qanday va qachon olib tashlashni bilib oling)

Silostamid
Ismlar

IUPAC nomi N-Sikloheksil-N-metil-4 - [(2-okso-1)H-kinolin-6-yl) oksi] butanamid
Identifikatorlar
CAS raqami	68550-75-4^Y
3D model (JSmol )	Interaktiv rasm
ChEMBL	ChEMBL34431
ChemSpider	2651
IUPHAR / BPS	5167
PubChem CID	2753
UNII	45S5605Q18^Y
CompTox boshqaruv paneli (EPA)	DTXSID3045140
InChI InChI = 1S / C20H26N2O3 / c1-22 (16-6-3-2-4-7-16) 20 (24) 8-5-13-25-17-10-11-18-15 (14-17) 9-12-19 (23) 21-18 / h9-12,14,16H, 2-8,13H2,1H3, (H, 21,23) Kalit: UIAYVIIHMORPSJ-UHFFFAOYSA-N
Jilmayganlar CN (C1CCCCC1) C (= O) CCCOC2 = CC3 = C (C = C2) NC (= O) C = C3
Xususiyatlari
Kimyoviy formulalar	C₂₀H₂₆N₂O₃
Molyar massa	342.439 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari

Silostamid a PDE3 inhibitori.^[1]

Adabiyotlar

^ De Jonge, HR; Miloddan avvalgi Tilli; Hogema, BM; Pfau, DJ; Kelley, Kaliforniya; Kelley, MH; Melita, AM; Morris, MT; Viola, RM; Forrest, JN (2013). "3-turdagi fosfodiesterazning CGMP inhibatsiyasi - bu S-tipli Natriuretik peptid Shark rektal bezida CFTR ni faollashtiradigan asosiy mexanizm". Amerika fiziologiya jurnali. Hujayra fiziologiyasi. 306: C343-C353. doi:10.1152 / ajpcell.00326.2013. PMC 3919979. PMID 24259420.

Fosfodiesteraza inhibitörleri
PDE1	MMPX SCH-51866 Vinpotsetin
PDE2	BAY 60-7550 Karbazeran EHNA Oksindol XDP
PDE3	Adibendan Amrinon (inamrinon) Anagrelid Benafentrin Bukladesine Karbazeran Silostamid Silostazol Enoksimon Imazodan KMUP-1 Meribendan Milrinone Olprinone Parogrelil Pimobendan Pumafentrin Kvazinon RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverin
PDE4	Apremilast Arofilin Atizoram Benafentrin Katramilast CC-1088 CDP-840 CGH-2466 Cilomilast Sipamfilin Krizaborol Denbutilin Difamilast Drotaverin Etazolat Filaminast Glaucin HT-0712 ICI-63197 Indimilast Irsogladin Lavamilast Lirimilast Lotamilast Luteolin Mesembrenone Mesembrin Mesopram Oglemilast Piklamilast Pumafentrin Revamilast Ro 20-1724 Roflumilast Rolipram Ronomilast RPL-554 RS-25344 Tetomilast Tofimilast YM-976 Zardaverin
PDE5	Asetildenafil Aildenafil Avanafil Beminafil Benzamidenafil Dasantafil Ikariin Gisadenafil Gomosildenafil Lodenafil Mirodenafil MY-5445 Nitrosoprodenafil Norkarbodenafil SCH-51866 Sildenafil Sulfoaildenafil T-0156 Tadalafil Udenafil Vardenafil
PDE7	BRL-50481
PDE9	BAY 73-6691 PF-04447943 Paraksantin
PDE10	Balipodekt Mardepodekt Papaverin TC-E 5005 Tofisopam
PDE11	Miloddan avvalgi 11-38
Tanlanmagan	Aminofillin Kofein Xolin teofillinati CPX Dipiridamol Doksofilin Enfrofilin Ibudilast IBMX Luteolin Pentoksifillin Propentofilin Teobromin Teofillin Zaprinast
Saralanmagan	Diazepam Diprofilin DPCPX Furafilin Lisofillin MDL-12330A Moxaverin Oxagrelate Pentifilin Proksifillin Quercetin Satigrel Tolafentrin Trapidil
Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari

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