T-0156 - T-0156 - Wikipedia

T-0156
Ismlar
	IUPAC nomi Metil 2 - [(2-metilpiridin-4-il) metil] -1-okso-8- (pirimidin-2-ilmetoksi) -4- (3,4,5-trimetoksifenil) -2,7-naftiridin-3- karboksilat
	Boshqa ismlar T0156; Tokris-1676
Identifikatorlar
3D model (JSmol )	Interaktiv rasm;
ChemSpider	5175; 8027754 (HCl);
IUPHAR / BPS	5275;
PubChem CID	5368; 9852041 (HCl );
	InChI InChI = 1S / C31H29N5O7 / c1-18-13-19 (7-11-32-18) 16-36-27 (31 (38) 42-5) 25 (20-14-22 (39-2) 28) 41-4) 23 (15-20) 40-3) 21-8-12-35-29 (26 (21) 30 (36) 37) 43-17-24-33-9-6-10-34- 24 / h6-15H, 16-17H2,1-5H3 Kalit: JEMJAABFSYOLAP-UHFFFAOYSA-N;
	Jilmayganlar CC1 = NC = CC (= C1) CN2C (= C (C3 = C (C2 = O) C (= NC = C3) OCC4 = NC = CC = N4) C5 = CC (= C (C (= C5) OC ) OC) OC) C (= O) OC;
Xususiyatlari
Kimyoviy formulalar	C31H29N5O7
Molyar massa	583.601 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

T-0156 a fosfodiesteraza 5 inhibitori.^[1]^[2]

Adabiyotlar

^ Parlak, A; Yildirim, S; Bagcivan, men; Durmus, N (oktyabr 2012). "Ovalbumin bilan sezgirlangan Gvineya cho'chqa traxeyasida NO / cGMP yo'lini ta'sir qiluvchi yangi agentlarning roli". Eksperimental o'pka tadqiqotlari. 38 (8): 420–6. doi:10.3109/01902148.2012.719281. PMID 23030645. S2CID 22720639.
^ Santos, AI; Karreyra, BP; Nobre, RJ; Carvalho, CM; Araujo, IM (2014). "Fosfodiesteraza 5 ning inhibatsiyasi bilan asab hujayralari hujayralarining ko'payishini rag'batlantirish". Stem Cells International. 2014: 878397. doi:10.1155/2014/878397. PMC 3914480. PMID 24550991.

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[1] Parlak, A; Yildirim, S; Bagcivan, men; Durmus, N (oktyabr 2012). "Ovalbumin bilan sezgirlangan Gvineya cho'chqa traxeyasida NO / cGMP yo'lini ta'sir qiluvchi yangi agentlarning roli". Eksperimental o'pka tadqiqotlari. 38 (8): 420–6. doi:10.3109/01902148.2012.719281. PMID 23030645. S2CID 22720639.

[2] Santos, AI; Karreyra, BP; Nobre, RJ; Carvalho, CM; Araujo, IM (2014). "Fosfodiesteraza 5 ning inhibatsiyasi bilan asab hujayralari hujayralarining ko'payishini rag'batlantirish". Stem Cells International. 2014: 878397. doi:10.1155/2014/878397. PMC 3914480. PMID 24550991.

[1]

[2]

Fosfodiesteraza inhibitörleri
PDE1	MMPX SCH-51866 Vinpotsetin
PDE2	BAY 60-7550 Karbazeran EHNA Oksindol XDP
PDE3	Adibendan Amrinon (inamrinon) Anagrelid Benafentrin Bukladesine Karbazeran Silostamid Silostazol Enoksimon Imazodan KMUP-1 Meribendan Milrinone Olprinone Parogrelil Pimobendan Pumafentrin Kvazinon RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverin
PDE4	Apremilast Arofilin Atizoram Benafentrin Katramilast CC-1088 CDP-840 CGH-2466 Cilomilast Sipamfilin Krizaborol Denbutilin Difamilast Drotaverin Etazolat Filaminast Glaucin HT-0712 ICI-63197 Indimilast Irsogladin Lavamilast Lirimilast Lotamilast Luteolin Mesembrenone Mesembrin Mesopram Oglemilast Piklamilast Pumafentrin Revamilast Ro 20-1724 Roflumilast Rolipram Ronomilast RPL-554 RS-25344 Tetomilast Tofimilast YM-976 Zardaverin
PDE5	Asetildenafil Aildenafil Avanafil Beminafil Benzamidenafil Dasantafil Ikariin Gisadenafil Gomosildenafil Lodenafil Mirodenafil MY-5445 Nitrosoprodenafil Norkarbodenafil SCH-51866 Sildenafil Sulfoaildenafil T-0156 Tadalafil Udenafil Vardenafil
PDE7	BRL-50481
PDE9	BAY 73-6691 PF-04447943 Paraksantin
PDE10	Balipodekt Mardepodekt Papaverin TC-E 5005 Tofisopam
PDE11	Miloddan avvalgi 11-38
Tanlanmagan	Aminofillin Kofein Xolin teofillinati CPX Dipiridamol Doksofilin Enfrofilin Ibudilast IBMX Luteolin Pentoksifillin Propentofilin Teobromin Teofillin Zaprinast
Saralanmagan	Diazepam Diprofilin DPCPX Furafilin Lisofillin MDL-12330A Moxaverin Oxagrelate Pentifilin Proksifillin Quercetin Satigrel Tolafentrin Trapidil
Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari

Ismlar

IUPAC nomi Metil 2 - [(2-metilpiridin-4-il) metil] -1-okso-8- (pirimidin-2-ilmetoksi) -4- (3,4,5-trimetoksifenil) -2,7-naftiridin-3- karboksilat
Boshqa ismlar T0156; Tokris-1676
Identifikatorlar
3D model (JSmol )	Interaktiv rasm
ChemSpider	5175 8027754 (HCl)
IUPHAR / BPS	5275
PubChem CID	5368 9852041 (HCl )
InChI InChI = 1S / C31H29N5O7 / c1-18-13-19 (7-11-32-18) 16-36-27 (31 (38) 42-5) 25 (20-14-22 (39-2) 28) 41-4) 23 (15-20) 40-3) 21-8-12-35-29 (26 (21) 30 (36) 37) 43-17-24-33-9-6-10-34- 24 / h6-15H, 16-17H2,1-5H3 Kalit: JEMJAABFSYOLAP-UHFFFAOYSA-N
Jilmayganlar CC1 = NC = CC (= C1) CN2C (= C (C3 = C (C2 = O) C (= NC = C3) OCC4 = NC = CC = N4) C5 = CC (= C (C (= C5) OC ) OC) OC) C (= O) OC
Xususiyatlari
Kimyoviy formulalar	C₃₁H₂₉N₅O₇
Molyar massa	583.601 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari