Thiomuscimol - Thiomuscimol

Thiomuscimol
Thiomuscimol.svg
Ismlar
IUPAC nomi
5- (aminometil) -1,2-tiazol-3-ol
Identifikatorlar
3D model (JSmol )
ChemSpider
Xususiyatlari
C4H6N2OS
Molyar massa130.17 g · mol−1
Erish nuqtasi140 ° C (parchalanish)[1]
Kislota (p.)Ka)6.06 ± 0.03, 8.85 ± 0.04 (H2O, 21 ° C)
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari

Thiomuscimol a GABAA retseptorlari agonist qaysi tizimli ravishda bog'liq bo'lgan muskimol.[2]

Adabiyotlar

  1. ^ Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg, Tomas; Pilotti, Anne-Mari; Anthonsen, T. (1976). "GABA ning strukturaviy analoglari. 5-Aminometil-3-izotiyazolol (Thiomuscimol) sintezi". Acta Chemica Scandinavica. 30b: 781–785. doi:10.3891 / acta.chem.scand.30b-0781.
  2. ^ Krogsgaard-Larsen, P; Hjeds, H; Kertis, DR; Lodge, D; Johnston, GA (1979). "Dihidromuscimol, tiomuscimol va unga aloqador heterosiklik birikmalar GABA analoglari sifatida". Neyrokimyo jurnali. 32 (6): 1717–24. doi:10.1111 / j.1471-4159.1979.tb02284.x. PMID  448364.